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CBN Sleep Study Shows Promising Effects of CBN
If you’ve ever wondered why that old stash of cannabis tucked away in the back of your drawer was rumored to have certain effects, you’re not alone—scientists have been curious about this cannabis folklore for ages. Recent research from the University of Sydney’s Lambert Initiative for Cannabinoid Therapeutics is shedding light on cannabinol (CBN), a cannabis component that’s generating interest for its unique properties. So, What’s CBN Anyway? We’re all pretty familiar with CBD and THC by now. But CBN is a lesser-known cannabinoid that forms when THC breaks down over time. Picture it as the “chilled-out” version of THC’s original form, mellowed with age. Unlike THC, CBN doesn’t leave you feeling “high” or intoxicated. Researchers are increasingly interested in CBN for its potential to influence overall wellness, and this new study is among the first to explore its effects using objective measurements in preclinical models. What Did the Scientists Actually Find? In their experiments, researchers gave rats purified CBN and then monitored their resting patterns with specialized equipment. The results indicated changes in rest-related behavior and cycles. The study provides a foundation for further exploration into how cannabinoids like CBN interact with the body’s endocannabinoid system and natural rhythms. (Note: These preliminary findings in animal models do not necessarily translate to humans and are not indicative of the effects of any specific product.) What’s the Big Deal About REM and Non-REM Sleep? REM sleep is considered important for cognitive and emotional processes, while non-REM sleep is associated with overall rest and recovery. The study found that CBN influenced both types of sleep cycles in rats. More research is needed to determine how these findings could translate to humans and general wellness routines. And the Best Part—It’s Non-Intoxicating! Unlike THC, CBN isn’t going to cause intoxicating effects. It doesn’t activate CB1 receptors in the brain the way THC does. Researchers also observed that a metabolite (a kind of “breakdown buddy” created when your body processes CBN) had an effect on these receptors. This suggests that CBN’s interaction with the body may be more complex than originally understood. What’s Next for CBN Research? What about humans? The research team has a parallel human trial underway (not yet published) to explore CBN’s effects. Early reports support further investigation, but additional research is needed to understand its full potential and optimal applications. In the future, CBN may be studied in combination with other cannabis compounds or supplements to explore possible synergies. The scientists at the Lambert Initiative are already working on a preclinical drug discovery program around CBN, exploring new ways to unlock its potential. Takeaway: CBN Is the New Cannabinoid in the Spotlight While THC and CBD have received significant attention in recent years, CBN is emerging as an intriguing compound for cannabis researchers. Early results in preclinical models provide a starting point for understanding its possible contributions to wellness. Stay tuned as more research emerges on this unique cannabinoid!
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The Entourage Effect
If you’re new to cannabis, you may not know about THC, CBD, and terpenes, but they’re an integral part of the cannabis plant that all novice and expert consumers can learn about. Even if you’re just entering the cannabis world, it’s likely you’ve heard about various ratios. But the real question is: why do so many cannabis enthusiasts care about ratios? Different cannabinoids (THC, CBD, THCa, etc.) are thought to work in tandem when consumed—a process known as the entourage effect. The cannabis Entourage Effect is the idea that various compounds found in the cannabis plant act in synergy together, and that they can have unique effects when used together compared to isolated compounds. What is the Entourage Effect? The Entourage Effect is the concept that molecules that occur together in nature may interact in a way that creates unique outcomes. With cannabis, this means that capturing a broad range of plant compounds may be different from consuming isolated cannabinoids. Cannabis contains many interesting compounds such as terpenes, cannabinoids, cannabinoid acids, as well as phytonutrients. These molecular compounds are also naturally found in other plants and insects. Terpenes are just one aspect of the cannabis plant: the natural oils which are accompanied by a distinct aroma and viscosity. Terpenes and cannabinoids (such as CBD and THC) may interact to produce unique experiences. Lab and user-based studies reveal that while CBD or THC can work independently, they can often create different outcomes when taken in combination. Entourage Effect with CBD & THC When you choose a specific ratio, especially with naturally occurring terpenes, these combinations have the potential to create distinct experiences. The Entourage Effect is one of the leading theories influencing cannabis research worldwide. Some research suggests that terpenes, for example, can influence how cannabinoids interact with the body’s cannabinoid receptors, and that some combinations may produce varied effects. This is what the Entourage Effect is all about! The way CBD and THC work together is why our products may complement your wellness goals. Just like a great teammate, these two cannabinoids can work together to offer a broad experience. It should be noted that everyone’s body is different, so a 1:3 CBD:THC ratio might be preferred by one person, whereas another might favor a 3:1 CBD:THC ratio or a 30:1 CBD:THC ratio. CBD may influence the experience of THC, creating options for different preferences. The Endocannabinoid System & Entourage Effect The endogenous cannabinoid system, also known as the endocannabinoid system (ECS), is involved in physiological processes including appetite, mood, and memory. The ECS consists of two primary cannabinoid receptors: CB1 receptors (most concentrated in the central nervous system and brain) and CB2 receptors (abundant in the cardiovascular, gastrointestinal, and peripheral nervous systems). The natural cannabinoids and phytonutrients found in cannabis can interact with these signal receptors of the ECS. Cannabinoids and naturally-occurring endocannabinoids interact with the CB1 and CB2 receptors found throughout our bodies, much like a system of locks and keys. If you think of cannabinoids such as THC, CBD, or CBN as the keys, then the CB1 & CB2 receptors are the corresponding locks that they fit into. These interactions drive modern research into cannabinoids and will lead to future discoveries as research on the cannabis plant continues to grow. The effects of cannabinoids vary depending on the location of the cannabinoid receptors that they stimulate. These receptors are common in our limbic system (the part of the brain that affects memory, cognition, and psychomotor performance) and our mesolimbic pathway (associated with feelings of reward), and are also widely distributed throughout the body. Products that capture the whole essence of the plant and provide a full spectrum of the plant’s cannabinoids and natural terpene profile may have broad interactions with our endocannabinoid system. Whole Plant Full Spectrum™ Products Papa & Barkley is committed to creating wellness products that adhere to high quality standards. It is our belief that cannabis is an individualized experience. Different bodies may respond to different ratios of cannabinoids. We believe that optimal experiences can involve the use of both CBD, the non-intoxicating compound, and THC. Each person’s body and endocannabinoid system is unique, with different needs and receptors. Cannabis is not one-size-fits-all. We also believe that optimal effects may require the use of both CBD, the non-intoxicating compound in cannabis, and THC, its intoxicating component. Papa & Barkley offers a suite of products in different ratios, allowing you to select the best option for your personal preferences. At Papa & Barkley, we’re known for our award-winning Releaf Balm, but we’re so much more than that. The creation of our balm allowed us to branch out and create Whole Plant Full Spectrum™ cannabis wellness products that can complement your wellness routine. Looking for products to use after a workout? Try our Releaf Balm or Body Oil – the whole plant and essential oils are suitable for daily use. Want to unwind and support your wellness goals? We have a variety of ratio options in tinctures and capsules. Want to make your hike even better? Grab a gummy and hit the trail! No matter what you’re looking for, we’re here to support your wellness every day.
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Debunking Myths: Top 6 CBD Misconceptions & What You Need To Know
Some of the information you may see online about CBD is more myth than fact. Here are the top 6 myths about CBD and the truth about them!
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Everything You Need to Know about THCa vs THC
THCa is the non-psychoactive cannabinoid found in raw cannabis and live cannabis plants. Unlike THC, it doesn’t produce a euphoric effect, but still has plenty of benefits.
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What Are the Benefits of THC?
From pain relief to deeper sleep to better sex, here are the benefits of THC, a natural compound found in the cannabis plant
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CBD vs. THC: Which Is Right for Me?
Like all cannabinoids, THC and CBD interact with the body’s endocannabinoid system. We know that our body creates endocannabinoids that plant-derived cannabinoids supplement in order to regulate appetite, pain, mood and energy. So which one is right for you?
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What Is a CBD Tincture: A Comprehensive Guide for Beginners
What Is A CBD tincture? CBD tinctures are liquid extracts that make dosing easy and convenient. Learn about CBD tincture uses, CBD tincture benefits, and dosage.
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CBD For Pain: How CBD May Help
Many people use cannabinoids such as CBD and THC in their wellness routines. CBD and the ECS The endocannabinoid system (ECS) is a physiological network that may help the body stay in balance by regulating key functions such as sleep, appetite, stress, and physical sensations. The ECS accomplishes this task with the help of endogenous cannabinoids (neurotransmitters) such as anandamide and 2AG, and phytocannabinoids (external cannabinoids) such as THC and CBD. How CBD Interacts with the ECS Unlike THC, which binds to CB1 and CB2 cell receptors across the ECS, CBD has little binding affinity for these receptors. Instead, it is being studied for how it may stimulate various other receptors. For example, CBD is being researched in the context of TRPV1 receptors. CBD’s interaction with these receptors is an area of ongoing scientific study. CBD is also being studied for its potential to prolong the activity of endocannabinoids in the body. When these compounds finish their work, they are broken down by enzymes and recycled. Some research indicates that CBD may act as a breakdown inhibitor for at least one of these endocannabinoids (anandamide), potentially slowing down this process. Additionally, CBD is also being studied in relation to other physiological processes. Finding the Right Type of CBD Product for You Choosing the right CBD product for your needs is key. CBD products can be formulated in various ways, and the way they’re delivered to your ECS can alter how you experience their effects. Here are some product options to consider when selecting CBD products. CBD Oil CBD oils and tinctures are popular because they’re easy to use. When taken sublingually, oils may take effect in about 30 minutes, and their duration can vary, often lasting several hours. CBD Topicals CBD topicals are CBD-infused balms, lotions, creams, and salves that can be applied directly to the skin for localized use. Topicals are intended for use on the skin and are typically not absorbed into the bloodstream. Many people use CBD topicals as part of their post-workout or wellness routines. Just tuck a tub away in your gym bag or work bag and have an easy-to-use CBD topical on hand whenever you want it. CBD Softgels CBD softgels tend to take longer to take effect compared to oils. Because they go through the digestive process before taking effect, edible CBD products can take as long as 2 hours to kick in, with effects sometimes reaching their peak several hours after ingestion. The duration of effects from edibles may also be longer than with other methods. Some people report experiencing effects for much of the day. According to the CDC, 20% of Americans report experiencing ongoing discomfort. If you’re looking for a selection of high-quality and trustworthy CBD products, we're here to help!
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Curious About CBD for Sleep & Mood?
If you found your way to our blog, it’s a safe bet you’re interested in CBD, the “second cannabinoid” in the cannabis plant. In today’s post, we’re going to talk about something a little different: The potential of CBD oil as part of an evening routine. Sleep is something we all do, and yet it tends to get overlooked. That’s a shame, because as both clinical studies and a mountain of anecdotal evidence suggest, quality rest is important to our health and wellbeing. In fact, many therapists report that sleep quality—both their own and their patients’—is a primary concern in their practices. Here at Papa & Barkley, we care about overall wellness. In particular, our CBD drops and CBD softgels are crafted to support your wellbeing. Here’s some information you may find useful. CBD Oil and Your Body It’s estimated that 70 million Americans experience rest difficulties at any given moment. CBD is one of over 100 cannabinoids found in the cannabis plant. Do your own research (great start, you’re already reading this post), and consider consulting your healthcare provider to see if CBD fits with your wellness routine. Many therapists are aware of emerging CBD research and may be a good resource as you determine if CBD aligns with your preferences. Like other cannabinoids—of which there are over 100!—CBD interacts with the endocannabinoid system (ECS). Though it was only identified in the 1990s, it’s now believed that the ECS is one of the body’s principal regulatory networks, involved in processes such as: Appetite and metabolism Immune response Memory Communication between cells Proper sleep function The ECS sends and receives signals via natural chemicals called endocannabinoids. While these compounds are produced by the body, they’re strikingly similar to those produced by the cannabis plant. Cannabinoids such as CBD and THC interact with the ECS because they’re “speaking the same language” as the chemical signals in the ECS. Some researchers believe that this is why cannabinoids are being studied for their effects on sleep and relaxation. A large-scale study completed in 2019 explored CBD and its potential effects on rest, stress, and a sense of calm. The study focused in part on cortisol, a hormone typically associated with stress. The study concluded that CBD influenced cortisol levels. Choosing a CBD Product Try our CBD products in both drop and capsule format. Rest assured: Whichever format and strength you choose will be made from clean, all-natural CBD sourced from whole hemp flowers grown organically and sustainably, right here in the USA. Extracted using nothing more than gentle heat, pressure, and time, our full-spectrum CBD infusion is blended with pure MCT oil derived from coconut. That’s all! Because everyone’s a little different, sometimes it takes experimentation to find the optimal dosage. Your healthcare provider may be a good sounding board for your dosing plans. That’s one reason we offer our CBD products in three strengths: Mild, regular, and double strength. Whichever one you choose, we believe it can support your wellness journey. Remember: Quality rest is an important factor in supporting overall wellness. Do you have any other questions about CBD and rest? Just ask! We’re always happy to help.
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